Endocrine Abstracts

Laser Doppler fluorometry (LDF) is not an invasive method for diagnosing microcirculation in patients with diabetes mellitus, but the method needs to be improved. Evaluation of the LDF method in patients with diabetic neuropathy (DN) before and after the appointment of vitamin D (VD). Included patients with DM and VD deficiency, DM duration more then 5 years, HbA1c up to 9.0%, non-smokers, signed IC. LAKK-M was used. The value of perfusion was measured-M, σ- average modul...

Hypothesis: High doses of vitamin D (VitD) improves dermal microcirculation (MC) in diabetic patients with type 2 diabetes mellitus (T2DM) and diabetic neuropathy (DN).Purpose: To study the effect of different VD doses on skin MC values in T2DM patients and DN.Materials and methods: Sixty-two non-smoking T2DM patients with DN were randomized into two groups: Group 1 received 5000 IU (G1) and Group 2 received 40000 IU (G2) of cholec...

Background: In recent years, the role of vitamin D in improving the profile of inflammatory markers in order to prevent and treat diabetic neuropathy and microcirculation disorders has been actively studied.Aims: The research goal was to study the dynamics of inflammatory markers, clinical manifestations of diabetic peripheral neuropathy and laser Doppler flowmetry of skin microcirculation during treatment with various doses of cholecalciferol in patient...